Hypercholesterolemia, Hypocholesterolemia, Hypertriglyceridemia, In Vivo Kinetics-..
até
4x
de
R$ 91,28
sem juros
ou R$ 346,88
via Pix
Adicionar ao carrinho
Disponibilidade: 45 dias úteis
Estoque: 182 unidades
-
- 1x de R$ 365,14 sem juros
- 2x de R$ 182,57 sem juros
- 3x de R$ 121,71 sem juros
- 4x de R$ 91,28 sem juros
-
R$ 346,88
-
R$ 365,14
The past two decades have seen steady progress in our understanding of the pathogenesis of atherosclerosis. The role of low density lipoprotein (LOL) increase and of LOL receptor deficiency or malfunctions in familial hypercholesterolemia has been largely enlightened by the works of Brown and Goldstein. These authors postulated also that modification of LOL to a form recognized by the scavenger or acetyl-LOL receptor may be required for lipid loading of macrophage-derived foam cells in the lesions. A growing body of evidence suggests that oxidative modification of LOL could enhance its atherogenicity by its implication as a factor in the generation of foam cells. Thus, if the role of LOL in the pathogenesis of hypercholesterolemia was well established a great deal of information appears currently on new approaches such as the mechanisms leading to the accumulation of foam cells, the impact of LOL structural alterations, notably oxidation and the role of gene mutations of apolipoprotein Band/or LOL receptor The opening topic is devoted to these new avenues outlined in the field of hypercholesterolemia. The first part concerns the genetic aspects of atherosclerosis: mainly the genetics of apo 1 ipoprote ins, their transcriptional regulation, the amino acid mutations of the apo B gene and of the LOL receptor gene, the structural domains and the acylation sites of apoprotein B.
| ISBN | 9781468459067 |
| Autor(a) | Malmendier, Claude L. |
| Editora | Springer Publishing |
| Ano de edição | 2012 |
| Páginas | 454 |
| Acabamento | Brochura |
| Dimensões | 25,40 X 17,80 |
Produtos relacionados
-
Reaction Kinetics-..R$ 1.369,42R$ 1.095,54até 4x de R$ 273,88 sem jurosou R$ 1.040,76 via Pix20% Desconto -
Kinetics Of Drug Action-..R$ 912,92R$ 730,34até 4x de R$ 182,58 sem jurosou R$ 693,82 via Pix20% Desconto -
Fracture Kinetics Of Crack Growth-..R$ 456,42R$ 365,14até 4x de R$ 91,28 sem jurosou R$ 346,88 via Pix20% Desconto -
Chemical Kinetics Of Homogeneous Systems-..R$ 912,92R$ 730,34até 4x de R$ 182,58 sem jurosou R$ 693,82 via Pix20% Desconto
-
Categorias
Pague com
Selos
MYRE EDITORA, COMERCIALIZADORA, IMPORTADORA E DISTRIBUIDORA LTDA - CNPJ: 50.295.718/0001-20 © Todos os direitos reservados. 2026
