Organ Directed Toxicities Of Anticancer Drugs: Proceedings Of The First International Symposium On The Organ Directed Toxicities Of The Anticancer Dru-..
até
4x
de
R$ 282,18
sem juros
ou R$ 1.072,30
via Pix
Adicionar ao carrinho
Disponibilidade: 45 dias úteis
Estoque: 259 unidades
-
- 1x de R$ 1.128,74 sem juros
- 2x de R$ 564,37 sem juros
- 3x de R$ 376,24 sem juros
- 4x de R$ 282,18 sem juros
-
R$ 1.072,30
-
R$ 1.128,74
The addition of chemotherapy as an effective means to treat cancer has had a major impact on selected human malignancies. Due to a general inability to dif- ferentiate between normal and neoplastic cells, little selectivity exists in currently used oncolytic drugs. Consequently, significant toxicity to the patient is expected when systemic cancer chemotherapy is chosen as an appropriate therapeutic in- tervention. Much of this toxicity, such as damage to the bone marrow, gastroin- testinal tract, or hair follicles, is predictable based upon the fact that anticancer drugs kill actively dividing cells. These types of toxicities, while serious, are usually manageable and reversible and are, therefore, not often considered to be dose limiting. Unfortunately, several of the most important anticancer drugs also damage tissues in which the growth fraction is relatively small. Such toxicities can not be predicted based on the chemical structure of the drugs, are often not detected in preclinical studies, and are encountered frequently for the first time in clinical studies. Further, unlike most of the proliferative-dependent toxicities, the unpre- dicted toxicities are usually irreversible or only partially reversible upon cessation of drug administration. Because of this, the unpredicted toxicities are referred to as dose limiting. They represent a significant barrier to the ultimate efficacy of several of our most important anticancer drugs.
| ISBN | 9781461292050 |
| Autor(a) | Hacker, Miles P. |
| Editora | Springer Publishing |
| Ano de edição | 2011 |
| Páginas | 254 |
| Acabamento | Brochura |
| Dimensões | 23,40 X 15,60 |
Produtos relacionados
-
Organ Directed Toxicities Of Anticancer Drugs: Proceedings Of The First International Symposium On The Organ Directed Toxicities Of The Anticancer Dru-..R$ 1.410,92R$ 1.128,74até 4x de R$ 282,18 sem jurosou R$ 1.072,30 via Pix20% Desconto -
Cytotoxic Anticancer Drugs: Models And Concepts For Drug Discovery And Development: Proceedings Of The Twenty-Second Annual Cancer Symposium Detroit,-..
R$ 1.825,92R$ 1.460,74até 4x de R$ 365,18 sem jurosou R$ 1.387,70 via Pix20% Desconto -
Cytotoxic Anticancer Drugs: Models And Concepts For Drug Discovery And Development: Proceedings Of The Twenty-Second Annual Cancer Symposium Detroit,-..R$ 1.825,92até 4x de R$ 456,48 sem jurosou R$ 1.734,62 via Pix
-
Biochemical Modulation Of Anticancer Agents: Experimental And Clinical Approaches: Proceedings Of The 18Th Annual Detroit Cancer Symposium Detroit, Mi-..
R$ 1.410,92R$ 1.128,74até 4x de R$ 282,18 sem jurosou R$ 1.072,30 via Pix20% Desconto
-
Categorias
Pague com
Selos
MYRE EDITORA, COMERCIALIZADORA, IMPORTADORA E DISTRIBUIDORA LTDA - CNPJ: 50.295.718/0001-20 © Todos os direitos reservados. 2026
